Inhibition on platelet activation by shikonin derivatives isolated from Arnebia euchroma
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منابع مشابه
Anti-inflammatory and antimicrobial activity of Shikonin derivatives from Arnebia hispidissima (Lehm.) DC
Arnebia hispidissima roots have been used traditionally for the treatment of ulcers, boils, cuts, heart ailments and headache, fever, tongue and throat troubles. The purpose of this study was to characterize the most potent phytochemicals present in the ethyl acetate extract having anti-inflammatory and antimicrobial activity using carrageenan and CFA model. The observed results revealed that s...
متن کاملIn vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures
BACKGROUND Shikonin derivatives have cytotoxic and antitumor effects. This study aims to investigate the antitumor effects of acetylshikonin isolated from a Chinese medicinal herb Arnebia euchroma (Royle) Johnst. METHODS The 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to determine the in vitro antitumor effects of acetylshikonin on human lung adenocarcin...
متن کاملThe Healing Effect of Arnebia Euchroma Ointment versus Silver Sulfadiazine on Burn Wounds in Rat
BACKGROUND Burn is still a majordevastating condition in emergency medicine departments among both genders and all age groups in all developed and developing countries, leading to physical, psychological scars and economical burden. The present study aimed to determine the healing effect of topical treatment with Arnebia euchroma on second-degree burn wound in rats. METHODS Fifty rats were di...
متن کاملAntimicrobial and cytotoxic isohexenylnaphthazarins from Arnebia euchroma (Royle) Jonst. (Boraginaceae) callus and cell suspension culture.
The phytochemical investigation of the n-hexane extract from callus and cell suspension culture of Arnebia euchroma (Royle) Jonst. resulted in the isolation of nine isohexenylnaphthazarins: deoxyalkannin (1), alkannin (2), acetylalkannin (3), isobutyrylalkannin (4), β-hydroxyisovalerylalkannin (5), 2''-(S)-α-methylbutyrylalkannin (6), propionylalkannin (7), teracrylalkannin (8) and ac...
متن کاملWound Healing Effect of Arnebia euchroma gel on Excisional Wounds in Rats
BACKGROUND Wound healing is a complex process leading to regeneration of damaged skin tissue. Arnebia euchroma (AE) have many effective activities such as anti-inflammatory, antimicrobial, antioxidative, and anti-tumoral effects. The extract of AE has positive effects on burn wounds. This study is designed to investigate the healing effects of AE on excisional wounds in rats. MATERIALS AND ME...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
سال: 1995
ISSN: 0167-4889
DOI: 10.1016/0167-4889(95)00078-7